Latest malaria vaccine news
Recent stories and articles on malaria vaccine developments around the world
(Click on headline to read the full story.)
Malaria vaccine offers new mode of protection against disease
November 28, 2013 – A novel malaria vaccine developed at Oxford University has shown promising results in the first clinical trial to test whether it can protect people against the mosquito-borne disease.
University of Oxford
Africa: New push on malaria
November 22, 2013 – Malaria researchers believe that better coordination and new technologies, such as the use of vaccines and sophisticated disease mapping, can inject new life into the ambitious goal of eradicating the deadly illness.
A new danger to Africans
November 18, 2013 – Africans may become susceptible to a type of malaria that they had long been thought to be immune to because the parasite appears to be evolving, scientists said last week.
The New York Times
Technology roadmap resets targets on malaria vaccines
November 14, 2013 – More efficacious malaria vaccines and those that could eliminate the disease in different settings should be available by 2030, according to the 2013 Malaria Vaccine Technology Roadmap, announced today in The Lancet.
Malaria vaccine could be ready by 2015
October 22, 2013 – The world’s first malaria vaccine could be available within the next 18 months, marking a major advance in efforts to eradicate a disease that kills more than half a million people, many of them children, every year.
Hope for a malaria vaccine
October 13, 2013 – The most ambitious clinical trial of a malaria vaccine has shown some effectiveness in children over an 18-month period. While its efficacy is modest, it is nonetheless a significant advance in the long struggle to control a disease that kills some 600,000 people a year, mostly children under the age of 5.
The New York Times
The long war
October 12, 2013 – On October 8th researchers announced progress in developing a vaccine against malaria. GlaxoSmithKline (GSK), a British pharmaceutical firm, said it would seek regulatory approval next year for this vaccine, called RTS,S. GSK and its charitable partner, the PATH Malaria Vaccine Initiative, also revealed new data showing the vaccine’s effect in children. This is good news, but RTS,S will not vanquish malaria by itself.
A shot against malaria
October 11, 2013 – Even through a crackled cellular connection from Durban, South Africa, the optimism can be heard in Dr. David Kaslow’s mild-mannered voice. “It’s been a fairly long road. Twenty-plus years in development. There’s been a lot of twists and turns.”
The New Yorker
GSK malaria vaccine could be available in three years
October 8, 2013 – GSK is ready to take the first step in getting the vaccine to market after promising trial results showing it was effective in protecting children and babies from malaria for up to 18 months.
First malaria vaccine moves a step closer to approval
October 8, 2013 – A malaria vaccine studied in more than 15,000 African children has been found to reduce the number of cases of disease by 27 to 46 percent.
UK firm seeks to market world's first malaria vaccine
October 8, 2013 – British drug maker GlaxoSmithKline is seeking regulatory approval for the world's first malaria vaccine after trial data showed that it had cut the number of cases in African children.
Africa: Malaria vaccine candidate reduces disease over 18 months of follow-up in late-stage study
October 7, 2013 – Durban, South Africa — Results from a large-scale Phase III trial, presented today in Durban at the Multilateral Initiative on Malaria Pan African Conference, show that the most clinically advanced malaria vaccine candidate, RTS,S, continued to protect young children and infants from clinical malaria up to 18 months after vaccination.
Hope of malaria vaccine by 2015 after successful trials
October 7, 2013 – A vaccine against malaria could be introduced in the world's worst-hit countries in 2015, after the latest trial of a treatment produced by Britain's biggest drug company reduced the number of cases of the disease experienced by babies.
Old drug, new tricks to fight malaria in West Africa
September 11, 2013 – A new way of using an old drug is proving to be a breakthrough in combating seasonal malaria in West Africa, which kills tens of thousands of children every year according to Medicins Sans Frontieres (MSF).
Thomson Reuters Foundations
Knocking down the malaria causing parasite
August 22, 2013 – Targeting the malaria parasite’s ability to make an iron-containing molecule, haem, might help create a vaccine against the disease and also lead to novel drug therapies for blocking infection and transmission, according to research from a team of Indian scientists that was published recently in PLOS Pathogens.
A malaria vaccine works, with limits
August 12, 2013 – A new type of malaria vaccine gave 100 percent protection against infection to a small number of volunteers in recent tests—but under conditions that would be nearly impossible to reproduce in the countries where most malaria victims live.
The New York Times
Malaria vaccine shows early promise in clinical trials
August 8, 2013 – A malaria vaccine has shown promising results in early stage clinical trials, according to researchers.
Zapped malaria parasite raises vaccine hopes
August 8, 2013 – A malaria vaccine has become the first to provide 100% protection against the disease, confounding critics and far surpassing any other experimental malaria vaccine tested. It will now be tested further in clinical trials in Africa.
Children help researchers solve malaria vaccine puzzle
July 22, 2013 – Australian researchers have found promising new targets for a vaccine to prevent malaria, a disease that kills more than 600,000 people every year. Researchers at Melbourne's Burnet Institute and the Papua New Guinea Institute of Medical Research recently studied 200 children in PNG to see how their immune systems had responded to malaria parasites commonly found in the region.
The Sydney Morning Herald
Malaria eradication: is it possible? Is it worth it? Should we do it?
July 2013 – The malaria map is rapidly shrinking. In 1900, endemic malaria was present in almost every country. Nowadays, the disease has been eliminated in 111 countries and 34 countries are advancing towards elimination. Elimination is defined as the absence of transmission in a defined geography—typically a country. Successful malaria control programmes in the remaining 64 countries with ongoing transmission have helped to reduce global incidence by 17% and mortality by 26% since 2000. For the 34 eliminating countries, the reductions were 85% in incidence and 87% in mortality. This progress is encouraging, but is worldwide eradication of human malaria possible? If so, is it a worthwhile goal and should we commit to it?
The Lancet Global Health
Vivax malaria eradication: where are we now?
June 25, 2013 – The re-establishment of malaria eradication as an international goal has repositioned Plasmodium vivax on the malaria research agenda. Papers devoted to this species have more than doubled during the last decade, and in recent years, four scientific conferences have been devoted to this malaria species, the last one in May 2013, in Barcelona, Spain.
The Lancet Global Health Blog
A fresh start, back in Brazil, at 85
June 25, 2013 – Ruth and Victor Nussenzweig have reached a point in their careers when most scientist-couples probably would choose a well-deserved retirement. Based at New York University (NYU) in New York City, the Nussenzweigs, who are both 85—they have been married for 60 years—have already had long, successful, independent careers. While Ruth has focused on providing the basis for the development of a malaria vaccine, Victor concentrated on basic immunology, studying the structure and function of various immune components and the parasitology of malaria and Chagas disease.
GlaxoSmithKline launches Africa charity partnership
May 10, 2013 – Britain's biggest drug manufacturer has launched a new partnership with Save the Children to develop medicines to tackle child mortality in Africa.
Opinion pieces published in recognition of World Malaria Day
April 26, 2013 – Wednesday was World Malaria Day, observed annually on April 25. This year's theme was "Invest in the future: defeat malaria." The following is a summary of opinion pieces published in recognition of the day.
Crenshaw and Davis: Ending the scourge of malaria
April 26, 2013 – Although our nation is facing tough fiscal challenges, we have seen incredible returns on some of our investments, particularly in global health, and we simply cannot afford to turn our backs on these commitments now.
The Washington Times
Africa: Malaria - the ongoing fight against an old, adaptive foe
April 25, 2013 – As the global public health community solemnly marks World Malaria Day, attention turns to the human toll enacted by this deadly disease and the measures needed to eradicate it.
Anti-malaria vaccine a few tests away
April 25, 2013 – So far, over 30 vaccine candidates have been discontinued, and researchers are working to improve RTS,S in the hope that, by 2025, the world will have a malaria vaccine that reduces the disease by 80 per cent and protects for longer.
Hope for wiping out malaria vested in vaccines
April 25, 2013 – The last 10 years have seen significant gains in the fight against malaria. Around the world, cases of the disease have dropped—so too the number of deaths. But malaria still kills an estimated 660,000 people every year, most of them African children. The gains are fragile and could easily be reversed. On World Malaria Day, international Geneva correspondent, Vincent Landon, takes a look at where we are in the war on malaria and why new hope is vested in vaccines.
World Radio Switzerland
April 2013: World Malaria Day supplement
April 25, 2013 – Special supplement issued with The Independent on World Malaria Day.
US promotes active surveillance in global fight against malaria
April 24, 2013 – In the 13 years since the United Nations first marked April 25 as World Malaria Day, dramatic progress has been made in preventing, controlling and treating this deadly tropical disease. Experts believe that with improved surveillance and more diligent treatment efforts, the disease could be soon be eradicated.
Voice of America
Decade of Vaccines supplement features PATH contributors
April 18, 2013 – The journal Vaccine has published a special supplement dedicated to the Decade of Vaccines Global Vaccine Action Plan (GVAP) that features articles by PATH contributors and others on the GVAP strategic objectives and the opportunities and challenges associated with its implementation.
PATH press room
Crossing borders: Sub-Saharan Africa is focus of efforts to defeat a killer
March 24, 2013 – The face of malaria today is not children's author Theodor Seuss Geisel's "party gal Ann" but an African child. Malaria is the No. 1 killer of children under age 5.
The Sacramento Bee
Failing vaccine strategies need to be revamped
March 5, 2013 – New approaches are needed to reverse the trend of disappointing vaccines against HIV/AIDS, tuberculosis and malaria, argues biotech expert Thomas Egwang.
The quest to end malaria deaths by 2015: The search for an effective malaria vaccine
February 19, 2013 – Malaria is a treatable and preventable disease. However, the disease continues to claim lives, especially of children under five years of age and pregnant women.
Probing the malarial shape shifters
February 6, 2013 – Developing nano tools to study the parasites at the root of one of the world's greatest health threats.
MIT Industrial Liaison Program
Study of candidate malaria vaccine shows results in Ethiopia
February 6, 2013 – Scientists recently studied the nature of humoral immune responses to a malaria vaccine candidate in two Ethiopian ethnic groups living in malaria-endemic regions.
Vaccine News Daily
European Commission commits to fight against pregnancy-associated malaria
February 6, 2013 – The European Commission recently dedicated six million Euros toward the development of a candidate vaccine against pregnancy-associated malaria.
Vaccine News Daily
Bill Gates: Malaria can be eradicated
January 25, 2013 – Deadly diseases like malaria, tuberculosis and HIV that afflict the world's poorest the most can be eradicated, Microsoft founder Bill Gates said, but he worries austerity measures could clip some public funding.
Intractable malaria parasites made to thrive in human cell culture
January 21, 2013 – Much of what we know about the species of parasite responsible for the malaria widespread in Africa was learnt from studying the parasite's biology and gene expression in human red blood cells in vitro.
Scientists in Benin unveil enhanced malaria test
January 21, 2013 – Researchers in Benin say they have developed an improved method for detecting malaria parasites in mosquito vectors that could help yield better estimates of malaria transmission intensity in different settings.
New plans to improve malaria vaccine
January 19, 2013 – Scientists have started a new project to enhance the malaria vaccine, giving fresh impetus to the fight against the killer disease.
The East African
Here I am: Focus on malaria elimination—an interview with Dr. Roly Gosling
January 17, 2013 – This week, an important meeting on the monitoring and evaluation of malaria control policies is taking place. The Monitoring & Evaluation Reference Group (MERG) meeting, convened by the Roll Back Malaria Partnership is taking place in Namibia. This is an interview with Dr. Roly Gosling, an international expert on malaria who currently leads the Malaria Elimination Initiative at the University of California, San Francisco, Global Health Group.
Funding the future: Getting pharmaceuticals to tackle disease in Africa
January 17, 2013 – The RTS,S trial was not the success the public health community was hoping for—especially given that earlier trials showed 55% efficacy in children between 5 and 17 months. But it is still too early to give up on the vaccine, and more detailed results from the trial are set for release in 2014.
Think Africa Press
Africa: Working toward malaria eradication the "only viable long-term strategy"
January 10, 2013 – Dr. David Brandling-Bennett, deputy director of the malaria programme at the Bill & Melinda Gates Foundation, says that recent success in Zambia is proof that real progress can be made in the fight against malaria. AllAfrica recently spoke with him about current tools being used to fight the disease, the prospect for a vaccine and the hope of new drugs to accelerate progress.
PATH Malaria Vaccine Initiative and Inovio Pharmaceuticals partner to accelerate development of malaria vaccines and innovative delivery technologies
January 7, 2013 – The PATH Malaria Vaccine Initiative (MVI) and Inovio Pharmaceuticals, Inc. (NYSE MKT: INO) today announced a follow-on collaboration to advance malaria vaccine development and new vaccination delivery technologies.
Philadelphia Business Journal
Search for new malaria vaccine begins
January 7, 2013 – A new project to advance malaria vaccine development and new vaccine delivery technologies has been launched.
The Guardian Nigeria
PATH's malaria team partners with Inovio on new vaccine approach
January 7, 2013 – Seattle-based PATH is partnering with Inovio Pharmaceuticals Inc. to work on the global health organization’s Malaria Vaccine Initiative.
Puget Sound Business Journal
Don't mind the mosquito in 2013
January 4, 2013 – Scientists across the world and in Africa are making vast advances on vaccinations and treatments for diseases like malaria and tuberculosis.
The Africa Report